A reporter from the Science and Technology Daily learned from the University of Science and Technology of China that the micro-nano engineering laboratory of the School of Engineering Science of the school uses a femtosecond laser to guide the capillary force self-assembly compound processing method to realize the flexibility of the controllable three-dimensional micro-structure and the three-dimensional metal nanogap structure Prepared and realized the application in vortex optical chiral detection and high-sensitivity biochemical detection. The related research results have been published on Advanced Materials and Advanced Functional Materials.

Chiral micro-structures have important application potential in the fields of optics and mechanics, and can be used to construct a variety of optical and mechanical meta-materials. At present, there are still many difficulties in the flexible and controllable preparation of three-dimensional chiral micro-structures. The Micro and Nano Engineering Laboratory of University of Science and Technology of China has carried out long-term systematic research on femtosecond laser composite processing. In the previous work, they developed a new type of femtosecond laser composite processing method by combining femtosecond laser direct writing with capillary force self-assembly technology, which realized the preparation of complex multilevel polymer structures, and used micro-object manipulation. Application research has been carried out in many fields, such as preparation, micro-optics, and capillary-like micro-channel preparation.

Based on the previous work, the research team combined femtosecond laser direct writing with capillary force-driven self-assembly technology, and guided the direction and magnitude of capillary force by adjusting the spatial arrangement and structure size of the micro-structure. The multilevel chiral micro-structure shows the high flexibility and scalability of the method.

In addition, the research team also used this femtosecond laser composite processing method to successfully prepare a three-dimensional metal nanogap structure, and realized the high-sensitivity detection of the typical surface-enhanced spectroscopy SERS target R6G and the anti-cancer drug DOX. This research provides a new method for constructing metal nanogap structures on non-flat surfaces, and is expected to apply micro-fluid-based surface enhanced spectroscopy detection technology to precision medicine, real-time online detection and other fields.